Isabel Lucas was born on January 29, 1985, in Melbourne, Australia to a Swiss mother and an Australian father. She grew up in Cairns and went on to attend St. Monica's High School.

After enrolling at the Victoria College of Arts, Isabel Lucas was discovered by a theater agent who got her an audition for Home and Away, an Australian soap opera. Since producers didn’t feel the role for which she tried out was right for her, they created an entirely new character for the budding actress and Isabel Lucas found herself with her first television role.

From 2004 to 2006, Isabel Lucas played the role of Tasha Andrews in the hit show Home and Away. Shortly after wrapping up her part with the drama, Isabel Lucas, along with fellow protesters like actress Hayden Panettiere, traveled to visit a pod of dolphins off the coast of Japan in protest of dolphin killing practices taking place there.

After a brief hiatus from acting, the Aussie beaut returned in 2008 with the movie Daybreakers, costarring Ethan Hawke. Meanwhile, she was busy working on her 2009 flick, Transformers: Revenge of the Fallen, as well as her on role in the TV miniseries The Pacific.